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Differences between silver nanoparticles and silver ions

An increased interest in silver has reappeared in connection with the revealed its action in the body as a trace element necessary for the normal functioning of organs and systems, as well as powerful antibacterial and antiviral properties.

The active use of antibiotics caused an increase in allergic complications of antibiotic therapy, the toxic effect of antibiotics on internal organs and suppression of immunity, the appearance of fungal infections of the respiratory tract and dysbiosis after prolonged antibiotic therapy, as well as the emergence of resistant strains of pathogens to the antibiotics used.

The wide spectrum of antimicrobial action of silver, the lack of resistance to it in most pathogenic microorganisms, low toxicity, the absence of allergy to silver, and also good tolerance by patients contribute to an increased interest in silver in many countries of the world.
The action of silver is not specific for infection (like antibiotics), but for cell structure. Any cell without a chemically stable wall (bacteria and other organisms without a cell wall, such as extracellular viruses, have such a cellular structure) is exposed to silver.

Since mammalian cells have a completely different type of membrane (which does not contain peptidoglycans), silver has no effect on them.
Colloidal nanosilver is a new antibacterial product consisting of microscopic silver nanoparticles suspended in demineralized and deionized water. This is a product of high scientific technology.

More and more medical, hygienic and cosmetic products appear on the shelves of pharmacies and stores with silver nanoparticles or with silver ions. What is the difference between these two terms? Consumers often do not see the difference between silver nanoparticles and silver ions. Meanwhile, silver nanoparticles and silver ions have significant differences.
The difference in physical activity

A silver ion is one silver atom devoid of an electron. Because of this, the ion is always active, charged. An ion loses its activity due to the addition of a missing electron to itself and, as a result, ceases to be effective.

Depending on the composition in which they are present, the ions very quickly lose their activity due to the addition of a missing electron (by combining with the components of the composition) and cease to be effective. As soon as a silver ion combines with any substance, it ceases to be pure silver. It becomes part of another molecule, which no longer has the properties for which the ion was used in the composition of the product.
When applying a cosmetic product with silver ions to the surface of the epidermis, silver ions have time to neutralize a small number of bacteria, but they cannot overcome the epidermal barrier and completely destroy the foci of infections. In order for silver ions to get into the dermis, you need to use such an amount of a product that will have a negative effect on the body.

Silver nanoparticles are several thousand silver atoms combined into small crystals. They are balanced and neutral.
When applying a cosmetic product with silver nanoparticles to the surface of the epidermis, the nanoparticles do not tend to combine with other substances, since they do not have an imbalance in the number of electrons, which means they do not lose their activity for a long time and can have a longer beneficial effect. Silver nanoparticles easily penetrate into the inner layers of the skin and have a strong antibacterial effect precisely due to their size. This explains the differences between silver nanoparticles and silver ions in their activity and safety for humans:
 • nanoparticle - chemically inactive (but active against the simplest microorganisms);
 • ion - chemically active (in the process of searching for the missing electron).
The difference in the mechanism of antibacterial action

Silver ions act on the principle of inhibition of the vital functions of bacteria. Penetrating into the bacteria, silver ions act as toxins, poison the bacterium, thereby causing its death. Silver ions block the channels through which bacteria feed, exercising their vital functions. In the process of killing bacteria, a very large amount of ions is consumed in this way, so preparations with ions give a short-term and incomplete effect, since it is impossible to provide the right amount of ions in the dermis constantly and in the right amount.

Silver ions have low efficiency. In preparations, silver ions most often act as a preservative, and an antibiotic performs an antibacterial effect. Bacteria develop methods of protection against various antibiotics, preventing the penetration of the toxin in different ways or neutralizing it with special substances.

Silver nanoparticles act differently, they destroy the cell walls of bacteria, causing their instant death from physical destruction, and not from poisoning by toxin. Bacteria decay and die, and nanoparticles are able to function further. This way of killing bacteria does not leave them the opportunity to adapt, develop a defense mechanism and pass it on to future generations.

The undoubted advantage of nanoparticles compared to ions is that the surface coating on the nanoparticle is protective on the one hand, and on the other hand can act as a platform for the transfer of various active substances.

On the surface of nanoparticles, very important elements, various vitamins, beneficial acids (of natural origin) that are necessary for the skin can be carried into the dermis. Nanoparticles targetedly saturate the skin with the necessary substances, without affecting other organs and tissues.

To kill the same number of bacteria, silver ions in the solution need 100 times more than silver nanoparticles. Therefore, even a small amount of silver nanoparticles in the product can provide high efficiency. Silver nanoparticles can remain on the surface of the skin for a long time, silver ions are not capable of this, since they are very susceptible to ultraviolet radiation (sunlight).
The main differences between silver nanoparticles and silver ions

Silver Nanoparticle:
 • appearance - several thousand silver atoms combined into small crystals;
 • activity - chemically inactive (active against microorganisms);
 • mechanism of action - destroys the bacterial cell wall;
 • duration of action - long-term antibacterial effectiveness;
 • a way of protecting bacteria against nanoparticles has not been developed;
 • penetration into the dermis - easily penetrates the dermis due to the ultra-small size;
 • coating with special compounds - coated with active substances.

Silver ion:
 • appearance - one silver atom without an electron;
 • activity - chemically active (active in the process of searching for the missing electron);
 • mechanism of action - acts as a toxin;
 • duration of action - quickly loses effectiveness after the destruction of bacteria;
 • a method of protection in bacteria against ions - adapt;
 • penetration into the dermis - not all ions are able to cross the skin barrier;
 • coating with special compounds - no.

Thus, silver nanoparticles are much more efficient and safer than silver ions. As part of cosmetic and hygiene products, silver nanoparticles fully cope with their task, providing an antibacterial and antifungal effect.

All ARGITOS preparations are developed using special technology based on colloidal nanosilver using natural products and natural substances. They do not contain refined products, harmful and toxic components, do not cause allergies.

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